J.L. Simons in 'Authors'
Impact of Coenzyme Q10 Supplementation on Skeletal Muscle Respiration, Antioxidants, and the Muscle Proteome in Thoroughbred Horses
Coenzyme Q10 (CoQ10) is an essential component of the mitochondrial electron transfer system and a potent antioxidant. The impact of CoQ10 supplementation on mitochondrial capacities and the muscle proteome is largely unknown. This study determined the effect of CoQ10 supplementation on muscle CoQ10 concentrations, antioxidant balance, the proteome, and mitochondrial respiratory capacities. In a randomized […]
Long-chain Polyunsaturated Fatty Acid (PUFA) Supplementation Increases Levels in Red Blood Cells and Reduces the Prevalence and Severity of Squamous Gastric Ulcers in Exercised Thoroughbreds
Researchers assessed the relationship between plasma and RBC fatty acid composition and incidence and severity of squamous gastric ulcers when altered by short- or long-chain polyunsaturated fatty acid supplementation. Thirteen fit Thoroughbred horses in training were used in this study. Horses were evaluated by gastroscopy for squamous ulcer score, gastric pH, and blood fatty acid […]
Race Training Improves Skeletal Muscle Mitochondrial Volume Density, Function, and Capacity in Thoroughbreds
Racehorses are among the most elite athletes in the equine industry. However, little is known about mitochondrial adaptations to race training. To test the hypothesis that race training increases mitochondrial biogenesis and capacity, gluteus medius samples were collected from Thoroughbred horses (11 geldings, 2 mares) before and after 14 wk of early race training. Horses […]