L. Sordillo in 'Authors'
The Impact of N-acetyl Cysteine and Coenzyme Q10 Supplementation on Skeletal Muscle Antioxidants and Proteome in Fit Thoroughbred Horses
Horses have one of the highest skeletal muscle oxidative capacities amongst mammals, which, combined with a high glycolytic capacity, could perturb redox status during maximal exercise. We determined the effect of 30 d of oral coenzyme Q10 and N-acetyl cysteine supplementation (NACQ) on muscle glutathione (GSH), cysteine, ROS, and coenzyme Q10 concentrations, and the muscle […]
Antioxidant, Reactive Oxygen Species, and Coenzyme Q10 Concentrations and Expression of Electron Transfer Proteins in Thoroughbreds with Recurrent Exertional Rhabdomyolysis
In the mitochondria, complexes I and III of the electron transport system (ETS) generate reactive oxygen species (ROS) during exercise that are reduced by antioxidants to mitigate oxidative stress. Among these antioxidants are thiol-based antioxidants such as glutathione as well as coenzyme Q10 (CoQ10), which also transports electrons from complex I and II to complex […]