Resources
Exertional Rhabdomyolysis
Exertional rhabdomyolysis (ER) or “tying-up” has been recognized in horses for more than 100 years as a syndrome of muscle pain and cramping associated with exercise.
Glycogen Branching Enzyme Deficiency
Glycogen branching enzyme deficiency (GBED) is a disorder that causes muscle weakness in Quarter Horse and related breeds.
Muscle Atrophy
Muscle atrophy is not a single disease, it is simply the loss of muscle mass and it can have a range of clinical presentations and underlying causes. This complexity can make it a challenge to diagnose its underlying cause and to treat appropriately.
Myofibrillary Myopathy
Myofibrillar myopathy or MFM is a term used to describe a new disease our research group has identified in horses, particularly in Arabian and Warmblood horses.
Myosin Heavy Chain Myopathy
Horses of Quarter Horse-related breeds (American Paint, Appaloosa, crosses) that have a specific genetic mutation in the gene MYH1 can develop myosin heavy chain myopathy (MYHM).
Neuromuscular Diseases Related to Vitamin E
Equine diseases that develop due to vitamin E deficiency in young animals include nutritional muscle degeneration, a neurologic condition called equine neuroaxonal dystrophy (eNAD), or equine degenerative myeloencephalopathy (EDM).
Recurrent Exertional Rhabdomyolysis
Recurrent exertional rhabdomyolysis (RER) is an intermittent form of tying-up in horses that appears to involve an abnormality in intracellular calcium regulation as the possible cause.
Seasonal Pasture Myopathy
“Seasonal pasture myopathy” (SPM) or “atypical myopathy” (AM), is a devastating equine muscle disease which is fatal in over 90% of cases.
Shivers
Shivers or shivering is a chronic neuromuscular syndrome in horses that has been recognized for centuries.
Type 1 Polysaccharide Storage Myopathy
Type 1 polysaccharide storage myopathy (PSSM) is the form of PSSM caused by the genetic mutation in the glycogen synthase 1 gene.
Type 2 Polysaccharide Storage Myopathy
Type 2 polysaccharide storage myopathy (PSSM) represents one or more other forms of a muscle disease that are characterized by abnormal staining for muscle glycogen in microscopic examination of muscle biopsies.