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Kentucky Equine Research continually conducts studies at its 150-acre research facility. Some of these results are presented at industry conferences or shared in peer-reviewed journals. Review some of our findings from the past 30 years below.
November 05, 2021

The Impact of N-acetyl Cysteine and Coenzyme Q10 Supplementation on Skeletal Muscle Antioxidants and Proteome in Fit Thoroughbred Horses

Horses have one of the highest skeletal muscle oxidative capacities amongst mammals, which, combined with a high glycolytic capacity, could perturb redox status during maximal exercise. We determined the effect of 30 d of oral coenzyme Q10 and N-acetyl cysteine supplementation (NACQ) on muscle glutathione (GSH), cysteine, ROS, and coenzyme Q10 concentrations, and the muscle […]


November 10, 2020

Growth and Development of Thoroughbred Horses

Research into the growth and development of Thoroughbreds managed on commercial breeding farms is reviewed in this paper. Because horses are not meat-producing animals, less research has been performed quantifying growth, muscle, and bone development than with other production animals. However, variations in growth and development are linked with both value and wastage in young […]


January 17, 2020

Omeprazole Reduces Calcium Digestibility in Thoroughbred Horses

Proton pump inhibitors like omeprazole reduce nutrient digestibility in humans. This study determined the effect of omeprazole on the digestibility of diets containing limestone or marine-derived calcium (BMC) and to assess changes in blood parameters associated with gastric acid production and calcium status in horses. Thoroughbreds were used to evaluate the digestibility of diets containing […]


January 01, 2015

Comparison Of The Metabolic Responses Of Trained Arabians And Thoroughbreds During High- And Low-intensity Exercise

Prince, A., R. Geor, P. Harris, K. Hoekstra, S. Gardner, C. Hudson and J. Pagan. 2002. Comparison of the metabolic responses of trained Arabians and Thoroughbreds during high- and low-intensity exercise. Equine vet. J., Suppl. 34, 95-99. Read the abstract.


January 01, 2015

Growth of Australian Thoroughbreds Compared with Horses in New Zealand, America, England and India

Huntington PJ, Brown-Douglas CG, Pagan JD. Australian Equine Veterinarian, Volume 26, Issue 1, pp 80-92, Feb 2007. Access the article.


January 01, 2010

Effect Of Dietary Fats With Odd Or Even Numbers Of Carbon Atoms On Metabolic Response And Muscle Damage With Exercise In Quarter Horse–type Horses With Type 1 Polysaccharide Storage Myopathy

Borgia Lisa A; Valberg Stephanie J; McCue Molly E; Pagan JD; Roe Charles R (2010) Effect of dietary fats with odd or even numbers of carbon atoms on metabolic response and muscle damage with exercise in Quarter Horse-type horses with type 1 polysaccharide storage myopathy. American journal of veterinary research 2010;71(3):326-36.


January 01, 2009

Effect Of Triheptanoin On Muscle Metabolism During Submaximal Exercise In Horses

To compare effects of corn oil or a 7-carbon fat (triheptanoin) on acylcarnitine, lipid, and carbohydrate metabolism in plasma or muscle of exercising horses. Fatigue was not associated with depletion of citric acid cycle intermediates for either oil. Triheptanoin induced a significantly higher insulin secretion and did not appear to enhance muscle glycogen repletion.


January 01, 2008

Feeding Protected Sodium Bicarbonate Attenuates Hindgut Acidosis In Horses Fed A High Grain Ration

Feeding protected sodium bicarbonate attenuates hindgut acidosis in horses fed a high grain ration Pagan JD , Lawrence TJ , Lawrence LA , Huntington PJ Australian Equine Veterinarian 27(3), 53, 2008. Proceedings report of this research available here.


January 01, 2005

Fat Adaptation Affects Insulin Sensitivity And Elimination Of Horses During An 80 Km Endurance Ride

The present study tested the hypothesis that insulin sensitivity would be lower in horses adapted to sugar and starch than those adapted to fat and fiber during an endurance race.


January 01, 2005

Effects Of Oral Potassium Supplementation On Acid-base Status And Plasma Ion Concentrations Of Horses During Endurance Exercise.

To compare effects of oral supplementation with an experimental potassium-free sodium-abundant electrolyte mixture (EM-K) with that of oral supplementation with commercial potassium-rich mixtures (EM+K) on acid-base status and plasma ion concentrations in horses during an 80-km endurance ride.


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