Thoroughbred in 'Subject'
Race Training Improves Skeletal Muscle Mitochondrial Volume Density, Function, and Capacity in Thoroughbreds
Racehorses are among the most elite athletes in the equine industry. However, little is known about mitochondrial adaptations to race training. To test the hypothesis that race training increases mitochondrial biogenesis and capacity, gluteus medius samples were collected from Thoroughbred horses (11 geldings, 2 mares) before and after 14 wk of early race training. Horses […]
Antioxidant, Reactive Oxygen Species, and Coenzyme Q10 Concentrations and Expression of Electron Transfer Proteins in Thoroughbreds with Recurrent Exertional Rhabdomyolysis
In the mitochondria, complexes I and III of the electron transport system (ETS) generate reactive oxygen species (ROS) during exercise that are reduced by antioxidants to mitigate oxidative stress. Among these antioxidants are thiol-based antioxidants such as glutathione as well as coenzyme Q10 (CoQ10), which also transports electrons from complex I and II to complex […]
Heart Rates at the Trot on a Mechanical Walker Are Correlated to Cardiovascular Fitness in Thoroughbred Racehorses
The relationship between heart rate (HR) and velocity under saddle or on a treadmill can be used to estimate cardiovascular fitness in horses. Whether HR data gathered during other types of exercise can be used to estimate fitness is unknown. This study hypothesized that HR data collected on a mechanical walker could be used to […]
Changes in Red Blood Cell Fatty Acid Composition in Exercised Thoroughbred Horses Supplemented with Either KER EO-3 or Flax Oil for a Two-Month Period
The present study clearly demonstrates that daily intake of EPA and DHA from KER EO-3™ significantly increases RBC membrane EPA and DHA but that a similar amount of omega-3 in the form of ALA from flax (linseed) oil does not.
Growth and Development of Thoroughbred Horses
Research into the growth and development of Thoroughbreds managed on commercial breeding farms is reviewed in this paper. Because horses are not meat-producing animals, less research has been performed quantifying growth, muscle, and bone development than with other production animals. However, variations in growth and development are linked with both value and wastage in young […]
A Supplement Containing Marine-Derived Minerals Increases Bone Density in Thoroughbred Racehorses in Early Training
Bone density and strength are important for the long-term health and soundness of performance horses. Marine-derived mineral complexes improve bone density and strength in laboratory animals and humans. Additionally, nutrients without established requirements in horses, such as boron, silicon and vitamin C, may affect bone health. This study evaluated the effect of feeding a supplement […]
Omeprazole Reduces Calcium Digestibility in Thoroughbred Horses
Omeprazole (OM) is a proton pump inhibitor (PPI) that inhibits gastric acid secretion in horses and is the most popular treatment for EGUS. PPIs are also widely used in humans to treat acid-related conditions and have been associated with a reduction in the digestibility of several nutrients, including protein, fat, calcium (Ca) and iron. This […]
The Effect of Long-Chain Omega-3 Supplementation on Blood Serum Gamma-Glutamyl Transferase (GGT) Levels and Inflammation Post-Exercise in Thoroughbred Racehorses
Horses supplemented with EO-3™ had significantly lower (p<0.05) GGT levels 2 and 4 hours post-exercise compared to the control horses. This may have resulted from a reduction in inflammation observed post-exercise in the horses fed EO-3. Open Technical Bulletin
Mineral and Vitamin Supplementation Including Marine-Derived Calcium Increases Bone Density in Thoroughbreds
Bone quality is important for the long-term health and soundness of performance horses. In racehorses, insufficient bone density is associated with shin soreness, an important cause of lost training time and reduced starts, as well as other aspects of bone fatigue. Risks of injury during training are associated with insufficient bone density. Research has previously […]
Effect of Omeprazole and Calcium Sources on Calcium Digestibility in Thoroughbred Horses
Equine gastric ulcer syndrome (EGUS) is very common, with a prevalence estimated from 53% to 93%. A major contributor to its pathogenesis is excessive gastric acid. Omeprazole (OM) is a proton pump inhibitor (PPI) that inhibits gastric acid secretion in horses and is the most popular treatment for EGUS. PPIs are also widely used in […]