Furosemide Reduces the Energetic Cost of Exercise in Thoroughbreds Independent of its Effect on EIPH
J.D. Pagan, B.M. Waldridge, C. Whitehouse, L. Dalglish, S. Fuchs, M. Goff, Furosemide reduces the energetic cost of exercise in Thoroughbreds independent of its effect on EIPH. Journal of Equine Veterinary Science. Volume 33, Issue 5, Pages 328–329. (Proceedings of the 2013 Equine Science Society Symposium.)
Six fit Thoroughbred geldings (age 6.8 ± 1.2 y, BW 585 ± 19 kg) were used in a 3×3 Latin square trial to test the effect of furosemide on energetic efficiency during a standardized exercise test (SET) on an inclined (30) high-speed treadmill. The SET was performed at 1.7 m/s for 5 min, 4 m/s, 6 m/s, and 8 m/s for 2 min per step, and 9 m/s, 10 m/s, 11 m/s, 12 m/s, and 13 m/s for 1 min per step. The horses were not allowed access to water, hay or feed for 4 h before the SET. The treatment groups consisted of an untreated control (C) and two groups (F and FE) which received furosemide (0.5 mg/kg, IV) 4 h before the SET.